opendvp.pp.impute_marker_with_annotation#
- impute_marker_with_annotation(adata, target_variable, target_annotation_column, quantile_for_imputation=0.05)#
Change value of a feature in an AnnData object for rows matching a specific annotation.
Using a specified quantile value from the variable’s distribution.
- Return type:
Parameters:#
- adataad.AnnData
The annotated data matrix.
- target_variablestr
The variable (gene/feature) to impute.
- target_annotation_columnstr
The column in adata.obs to use for selecting rows to impute.
- quantile_for_imputationfloat, optional
The quantile to use for imputation (default is 0.05).
Returns:#
- ad.AnnData
A copy of the AnnData object with imputed values.